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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9581e59481d4364b0a35b3708a80411d11547d146404ce6346c5f048e5427f7' 
  AND token = 'dUmgywp6fk1+TCHr/8aRrpKQX1dgh7+Fw+mywZKMffw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}