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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01208e650fa826166220d91271543b3da6435e7a8bd5a71d9ab30ac48389103f' 
  AND token = 'c+rROA4N1kJ1EIVU5D95A1qhXoe2h28w+lL7Gn0vk20=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}