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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e0c7ea51cef3eaf718ca16b422eca9ddad8e43150edc0ae2f7601354af13119' 
  AND token = 'S26+WPQhImg7CGJmLHEfuC1+5MVZArzTVfjyV56QRgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}