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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a2bba3467c80ba7f5a7c1be67abfedf998ba4f86404f2a2a6c97322745f606' 
  AND token = 'tjCM0ZQYl3M1iZLU5aoP3AB+4yXUMkw9TL5tp2h4Lsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}