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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d392d9a54e49c0d2001df9e19cc00100f24e1c7da2bd4029ed6734eb78269b6' 
  AND token = 'LuagNBFTD1PQohCbE9WiqkvKKdQv2uSEDB/cq7sdwGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}