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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '764f5d836a430f55d8834adaf9363f933c6cead9278ec39ea4bd80dc22d80cf1' 
  AND token = 'zSukE/ob7y8UWe+7wM1hk6mjqyz75BWCbRVetlBHXsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}