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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0a2b377b4ca1f0a0bf82abb1312c47a29e898c470a257b6fccc483127848b2a' 
  AND token = 'QG9DVUXdmlESkdVU9uDKByBsJ2mGZFMiXCMgdwfBaes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}