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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f4e105bb20b054d37947ac70a9612ae1ee50f73d1ff518d777423538842649f' 
  AND token = 'sgwRdE/qIBDw373n9JJC7a8dyyhyA0pwpE4BntgAw1A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}