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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed65dd713103af47bc0850d38d2104325e89f5e5e2e1ff78b14340689c967c93' 
  AND token = '/sugfB4/sxqtgdSarujK5MSwvju0S6wBLE3FQ4B2Nqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}