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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03b8027559da96c7da391b0e6f616b116ea2b35c6e0479dfc2a2162c9824cb57' 
  AND token = 'tt3jKDo/Zyay+zztI6kjrP+G6TC0Re5gV8IuzdEdLaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}