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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '435cc793f89d90f543faf02334abed15cca00c6b3ee434a7c1c301927ac44b10' 
  AND token = 'fn03pZATHPSjArk9B13CXGFp2E+rrvguSiFTcvotnrk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}