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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0d692316be1246ef2ee341359dec48f134042105ec5e5cbe6e712469502152b' 
  AND token = 'ZA6oprg2j1vtZvkKoDEM1Spt43eXDChElsN/26P8PkI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}