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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42ee5eaa701d5135dcf09e53cb9cd87d609a07c71052e43ab8d2a3debcf13aff' 
  AND token = 'Q4lzf4JSap/AQ+S0QLp24d/X+QnTW8fizC7Y2TOK6iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}