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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd09e9102b0771c70d55999995ac62fb31f005abb9f33ffb08e33b9d1dc93a8d3' 
  AND token = 'H1UU9k5o/HnXE7le27fPEw2GfwDeFGSv+NYQdiJawrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}