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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9f67f8405aca1507c43ca8c025e48cea0f8cc0797399258ac7b80246517c359' 
  AND token = '7kXIH3Jir1z63x3+On7eBIwgBjdvbSMuqOGwakVcAvQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}