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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6e0da82300e66c6da2f6f2512db44d8385f7d4d75018b7f6b60c722660ddcdd' 
  AND token = 'OUi4MHrvYLgPTbCLkpCZgQH1I8zU8CJZLUtg9xFptnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}