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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6418bcd55300e8c01c6df77014b373ce0d2ccd5f38054a1c0faec34a4d8a1a4c' 
  AND token = '0BU5Fhk7qAfB33uC5L5v/Du1XUUqhNx5VjLyZE5dhcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}