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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7e90edbdacf2a2b2e5a7291b1aab2053938e321928d76fb3a64fb22ad381b3ea' 
  AND token = 'vkKJHjs/xn1gQ/XgNEkmn9/kXTfGsbolbloXE+UsI7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}