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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a3b6eed800d8b17766d326eedc44c26d9b9db9a80cc4e2b0c9d61b5b3dca9cd' 
  AND token = '3dYA0O1KYsJWBgzOKvyAJn+rAcvW4u40TIK0ALFbYm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}