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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4bd01733498b1b2ab210aeaf1c22916bf908c8c7e875352178b5c13b269de48' 
  AND token = 'v8RXfAoW7HAAOs+k7mhOE0sW8xQTGHjzkto3rfH7hfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}