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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74fda612bfd24399d16327b7f4d2d06be2efe09c23684069ca56c7b0d0c702a5' 
  AND token = 'xKKYuIEM6dCx5ngqk9wKAOh62rLA4zrkQ/0xNTnh5CY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}