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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8d6c71ae46ba4a052eaa92653f4114d69b50a71995c821505fcb4ce0b2e0983' 
  AND token = 'IPvFb0J/+2sbPnBltQHNLmfjnkAxwPmBEsJVS+c9Dqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}