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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73bf7280caf2d0508498d3669ae756455261d97fcfd89e22446fe02d538e1dd7' 
  AND token = 'cNB0ojXDllrW/Y2/5GICkVfYmUxdWSoHNk0G9ppUG5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}