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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '119852c381505c4f6a2be04a53f66cfd70320b78856a52390507bfbf85a66dcf' 
  AND token = 'nnI9EnmsV2aTLtQqmoFbBvQPopgVv/i2iueDaMTgQFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}