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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e7f0ccbade60ca6e86a3a919e6b477a2aec0d82fae6b6af621348e1525754b3' 
  AND token = 'O3gh4Lq/sPjGiMOaDRTfqrxZM8CeSV8eHr0aBTaBPZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}