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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e7b7778e66a0413b33155a1bad7e1a3be30bee57d06752fbf42ba4e45b0f87' 
  AND token = 'H76wGxDsriJGpSdn2+pXXvgY75QVv84Ps9B4ZTI5E+w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}