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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d4719a2964500d5fd8dd6f9073916ac2366ee522b4acfd7aacdaebcc1cca50a' 
  AND token = 'LGWMzVMP2u7Dts8iAdsqb9mS4ZHa0NLlRkwn8F9D3ho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}