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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '592686d26947f64b4d2634d44029bf6c5f4f54d1ccdf09c88db00bb6b6cccafc' 
  AND token = 'UCdT0txnW/fIUXBBUSbqJc26C2WYKsXq5Tx98Ra/qIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}