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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1fb49e8fb3f224f5bb0a1787ee832de6a0ed58cfddd76d5e954b8b92c775499' 
  AND token = '3owI5EvWBlwnser+qNo9ILuzxK7DHr5lbjxNCvqAeMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}