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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebc601d57e58733fc805c2ff1636d32a9c3b57edc9b6671ff0add0727c9e925d' 
  AND token = 'xo+tupdG2A5WHrpOdyXnrEuTeO1Qh2+B0NHn4GLd16o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}