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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '287105f601271dbbc01c840fc159177cfacb02374f0695ef1960c238b3d471fa' 
  AND token = 'SydVNxCqM0l4NMgw17ojmlEMcvksIcL4QbQ44sK+asc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}