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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41f708c802230b534c3caf2def3d12e001a19dc0a8682aee2c7d730747fdb056' 
  AND token = '+rX9UXUYfliVzMsE02SXGrZtLLbiab1P/pL3XLjenB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}