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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05654a0e9a3e08e2f5cc2f27f2d0c09cf2f1d68bae5f9f39ef75642ab4810680' 
  AND token = 'vr05B/iFaciPIDzvVAxH07MloWGyRr921/i3bnxG6MY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}