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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '857f8410d5467b7e835e6d0975b00c1b6e913ecdeb4fa4810e43ba5185505a8d' 
  AND token = 'SICJZBQyxDAz2+ty87AMrEFFqPIJpAKehh/TIt6+UYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}