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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dd9ac655b59aa92de3b8a1e6182be20785251283ed33ff9a133877e7e076287' 
  AND token = '2epCwGMIF0+s+iv87PEBzQc/ojAkozBQ3zPF6ogpcw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}