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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99bbce96486b1d03931df7fea5763628c7af7a30c388db69383f70dd9f0ea372' 
  AND token = 'pMc0nSVXi0mCoiTIAqnUjmRldx4REEm6iVlVvL1M3/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}