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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e436fd5204ee76129f6c6c21ba737262e64bce221a14e9090f3d2f928ce3cac' 
  AND token = 'Q3I/1C9nAOMuRi9n8SBABmgL5/JBLOZNssUWQwshmX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}