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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0125724fafa1f1bc40e725002e2fa034dadc408b6fd7dba8a37f1ab5bd290197' 
  AND token = 'MDOSwzzh520a5de58pVkV3/gzebb8I+A7L+QcOdvoYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}