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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45c56e53d470e4c3fcd066a0418bb0d50e326189c7cbb2513b02c9d53e169472' 
  AND token = 'AuAQDJ37p4d472RgJJbaTfmtzBovQP+a/WmC5uVeiDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}