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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7021ab12709622896893a803d822036b7bab4880f130f64fa1fb8f9cd5300ba' 
  AND token = '5MP+k1MIIBKg0TB+4CY/OCC0qTs8NahDOO2ZWtRMgYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}