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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ec189ee2fcee16b761e77efdfc00f5aa59f05f389ee5bea4532019e9da97d92' 
  AND token = 'BCq2AnvItIcaEDJ6munzQDV/wOtBVVWrZfkr2vjLfq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}