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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aec1ec0c280ccbe3a96d78cfcc10773928fb45d57631ee2dbd0e03eb02c11a0' 
  AND token = 'rKyBN7e9z+9p0mbyuw2+8IMXfNnHvfvo9kdT0Us+W4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}