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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffe4e2144d998fe8cfb47b67bc00b011ba66e57143c817adcc3745edbe48e693' 
  AND token = 'CZT7XNftnt+0TbaDYlpgv1apsnGrm8jHBEEGxRYkPZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}