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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfcb161c7629de69d1c243b874b8df2fb1a9a4d42d3e0120101a606cbf0094a1' 
  AND token = 'N7y+uNsfoDih6EME5+mb3Fvbeg0Z2GJzHWkIuxvYi/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}