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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b9bb705a9e9d556e4a81858c5f99b4cfc4d8802fb753a8e42f189f0d4049845' 
  AND token = 'V3/+3JWRv12wK1LMd6dcK/kAnCv4Jw+Kgz6W/V65IQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}