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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c9600371143d0b03e9a54e981c853cadd71aa1989fd8832f9740a08c15a3a52' 
  AND token = '+QN4r5OdTLqpfT/hOrxsv8KSUVlrxiRDeHS9qoVO05g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}