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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e5f1ddae21ed0c1f0db6c018cda69ad71fb1612d744651eb142ebbc9ce052d3' 
  AND token = 'iAzkZt9ZLK8fQjjv0LUnSZJV91wRIgc4WqhHsSdGnhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}