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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '281efc0124b64cbe40bdf4110eb25eec330832ad52b8d7d834d3b068acb79128' 
  AND token = '7dC+y3uZP7A3TsWK82wZb2j0CWZHRD1pYueHoCP/B/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}