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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03d836a0a7bdad4e5d76a296602b6721ca1dca49683b2e3ee7d50dbbdd843b21' 
  AND token = 'A15phaUB5VP1m1LB5SNBPOSu1oDDZnWbjncO6Fdtj/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}