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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d3dccb20668d727690eca94c9038845cf033c50d39cf0c1263c44fde949a3c3' 
  AND token = 'hxDqtSeR1v5jh9qJ4evlol4zEp/KjgxQKZDL47h24ko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}